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2002 Medicinal Chemistry Award
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F. I. Carroll

Short curriculum vitae

 

Dr. Carroll received a B.S. degree in chemistry from Auburn University in 1957. After receiving a Ph.D. degree in chemistry from the University of North Carolina at Chapel Hill in 1961, he joined the Research Triangle Institute where he moved from Research Chemist to Director of Organic and Medicinal Chemistry to Vice President of Chemistry and Life Sciences.

Dr. Carroll is a longstanding member of the American Chemical Society, is a Fellow of the AAAS and the AAPS, and is a member of a number of other professional organizations. His activities include service on the Long-Range Planning Committee of the Medicinal Chemistry Section of the American Chemical Society as well as service on the American Chemical Society Awards Committee. He served on the Editorial Advisory Board of the Journal of Medicinal Chemistry from 1995–1999 and is presently Medicinal Chemistry Section Editor for Drug Development Research. For many years he has provided service and advice to the National Institute on Drug Abuse and has been a member of several study sections.

Dr. Carroll has won national and international recognition as a medicinal chemist who has made distinguished contributions to many research areas, in particular the development of the 3-phenyltropane class of compounds as potential treatment agents for cocaine abuse. One of the 3-phenyltropane analogs (RTI-55) is also in phase III clinical trial as a diagnostic agent for Parkinson's disease. In his effort to develop agents for treating and preventing drug abuse, he has applied combinatorial methods in developing new structural types of opioid kappa receptor-selective antagonists and recently developed new nicotinic receptor antagonists.

Dr. Carroll's research efforts have resulted in 359 scientific publications and 18 patents. He has trained 79 postdoctoral fellows. Among Dr. Carroll's awards are the Distinguished Lecturer Award from the North Carolina Section of the American Chemical Society (1993), the Herty Medal (2001), and the Southern Chemist Award (2000). In addition, Dr. Carroll was honored by the National Institute of Drug Abuse with the 1993 Pacesetter Award and a 1996 MERIT Award for his research on the biochemical mechanisms of the action of cocaine.

 

© 28th National Chemistry Symposium, 2001-02